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Congestive hepatopathy and acute pancreatitis as severe complications of mixed connective tissue disease.
- Source :
-
Clinical journal of gastroenterology [Clin J Gastroenterol] 2020 Jun; Vol. 13 (3), pp. 434-442. Date of Electronic Publication: 2019 Nov 19. - Publication Year :
- 2020
-
Abstract
- Mixed connective tissue disease (MCTD) causes multiple organ dysfunctions, such as joint swelling, pulmonary fibrosis and hypertension, and serositis, but hepatopancreatic complications are rare. Here, we report a case of young man who exhibited acute severe liver dysfunction. He also had impaired cardiac function: both ventriculi were hypokinetic, but pulmonary hypertension and pericarditis were not observed. Since his liver and cardiac function markedly improved after commencing furosemide and carperitide, we considered congestive hepatopathy due to MCTD and accompanying heart failure. Heart failure and congestive hepatopathy recurred and he was treated with diuretics and prednisolone, but he passed away by co-occurrence of acute hemorrhagic pancreatitis. Necropsy revealed chronic hepatic congestion but not accompanying autoimmune hepatitis and hepatic vasculitis. We should consider congestive hepatopathy and hemorrhagic pancreatitis as serious complications of MCTD.
- Subjects :
- Adult
Fatal Outcome
Heart Failure etiology
Humans
Liver pathology
Liver Diseases diagnostic imaging
Liver Diseases pathology
Male
Mixed Connective Tissue Disease pathology
Pancreatitis diagnostic imaging
Skin pathology
Tomography, X-Ray Computed
Liver Diseases etiology
Mixed Connective Tissue Disease complications
Pancreatitis etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1865-7265
- Volume :
- 13
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinical journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 31745825
- Full Text :
- https://doi.org/10.1007/s12328-019-01059-6