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Survival outcomes of mucosal melanoma in the USA.
- Source :
-
Future oncology (London, England) [Future Oncol] 2019 Dec; Vol. 15 (34), pp. 3977-3986. Date of Electronic Publication: 2019 Nov 14. - Publication Year :
- 2019
-
Abstract
- Background: Mucosal melanomas (MM) arise within the lining of the gastrointestinal (GI), genitourinary (GU) and head and neck (HN) systems.  Method: A retrospective analysis of the National Comprehensive Database identified 4,961 MM patients. Primary objective was to compare survival outcomes across the different locations.  Results: Overall survival for GI melanomas was significantly shorter than HN and GU melanomas. Median survival (95% confidence interval) was 19.5 (18.0-21.5), 26.4 (24.9-28.3), and 43.9 (38.8-47.8), months for GI, HN and GU cases, respectively (p<0.0001).  Conclusion: This is the largest study of MM in a US based population, demonstrating worse overall survival for GI MM in comparison to HN and GU melanomas.
- Subjects :
- Aged
Aged, 80 and over
Female
Follow-Up Studies
Gastrointestinal Neoplasms pathology
Gastrointestinal Neoplasms therapy
Head and Neck Neoplasms pathology
Head and Neck Neoplasms therapy
Humans
Kaplan-Meier Estimate
Male
Melanoma pathology
Melanoma therapy
Middle Aged
Sex Factors
Survival Rate
Treatment Outcome
United States epidemiology
Urogenital Neoplasms pathology
Urogenital Neoplasms therapy
Gastrointestinal Neoplasms mortality
Head and Neck Neoplasms mortality
Melanoma mortality
Mucous Membrane pathology
Urogenital Neoplasms mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1744-8301
- Volume :
- 15
- Issue :
- 34
- Database :
- MEDLINE
- Journal :
- Future oncology (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 31724885
- Full Text :
- https://doi.org/10.2217/fon-2019-0465