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Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies.

Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies.

Authors :
Costa G
De Luca MA
Piras G
Marongiu J
Fattore L
Simola N
Source :
Neural regeneration research [Neural Regen Res] 2020 May; Vol. 15 (5), pp. 802-816.
Publication Year :
2020

Abstract

Preclinical and clinical studies indicate that synthetic psychoactive substances, in addition to having abuse potential, may elicit toxic effects of varying severity at the peripheral and central levels. Nowadays, toxicity induced by synthetic psychoactive substances poses a serious harm for health, since recreational use of these substances is on the rise among young and adult people. The present review summarizes recent findings on the peripheral and central toxicity elicited by "old" and "new" synthetic psychoactive substances in humans and experimental animals, focusing on amphetamine derivatives, hallucinogen and dissociative drugs and synthetic cannabinoids.<br />Competing Interests: None

Details

Language :
English
ISSN :
1673-5374
Volume :
15
Issue :
5
Database :
MEDLINE
Journal :
Neural regeneration research
Publication Type :
Academic Journal
Accession number :
31719240
Full Text :
https://doi.org/10.4103/1673-5374.268895