Trending: Radioactive and Fluorescent Bimodal/Hybrid Tracers as Multiplexing Solutions for Surgical Guidance.

Authors :: van Leeuwen FWB
Schottelius M
Brouwer OR
Vidal-Sicart S
Achilefu S
Klode J
Wester HJ
Buckle T
Source :: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2020 Jan; Vol. 61 (1), pp. 13-19. Date of Electronic Publication: 2019 Nov 11.
Publication Year :: 2020
Abstract: By contributing to noninvasive molecular imaging and radioguided surgery, nuclear medicine has been instrumental in the realization of precision medicine. During the last decade, it has also become apparent that nuclear medicine (e.g., in the form of bimodal/hybrid tracers) can help to empower fluorescence-guided surgery. More specifically, when using hybrid tracers, lesions can be noninvasively identified and localized with a high sensitivity and precision (guided by the radioisotope) and ultimately resected under real-time optical guidance (fluorescent dye). This topical review discusses early clinical successes, preclinical directions, and key aspects that could have an impact on the future of this field.<br /> (© 2020 by the Society of Nuclear Medicine and Molecular Imaging.)

Language :: English
ISSN :: 1535-5667
Volume :: 61
Issue :: 1
Database :: MEDLINE
Journal :: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Publication Type :: Academic Journal
Accession number :: 31712326
Full Text :: https://doi.org/10.2967/jnumed.119.228684

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