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Diffuse variants of scalp lichen planopilaris: Clinical, trichoscopic, and histopathologic features of 40 patients.
- Source :
-
Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2020 Dec; Vol. 83 (6), pp. 1659-1667. Date of Electronic Publication: 2019 Nov 09. - Publication Year :
- 2020
-
Abstract
- Background: Fibrosing alopecia in a pattern distribution and cicatricial pattern hair loss are poorly recognized diffuse variants of lichen planopilaris (LPP).<br />Objectives: The medical features of 40 patients affected by a diffuse hair thinning associated with a long-lasting history of pruritus and erythema of the scalp and a histopathologic diagnosis of LPP were reviewed.<br />Methods: Clinical data, results of trichoscopy and histopathology, response to treatment, and follow-up were analyzed.<br />Results: There were 18 patients diagnosed with fibrosing alopecia in pattern distribution and 2 patients with cicatricial pattern hair loss. A new variant of diffuse LPP, named "lichen planopilaris diffuse pattern," was described in 20 individuals.<br />Limitations: Low number of cases due to rarity of the diseases.<br />Conclusion: In patients complaining of a long-lasting history of scalp erythema, itching/dysesthesia, and diffuse hair thinning, it is advisable to consider diffuse variants of LPP.<br /> (Copyright © 2019 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- 5-alpha Reductase Inhibitors administration & dosage
Administration, Oral
Administration, Topical
Adult
Aged
Alopecia Areata drug therapy
Alopecia Areata immunology
Alopecia Areata pathology
Biopsy
Cicatrix drug therapy
Cicatrix immunology
Cicatrix pathology
Dermoscopy
Disease Progression
Drug Therapy, Combination methods
Female
Fibrosis
Follow-Up Studies
Hair Follicle diagnostic imaging
Hair Follicle drug effects
Hair Follicle immunology
Humans
Hydroxychloroquine administration & dosage
Hydroxychloroquine therapeutic use
Immunosuppressive Agents administration & dosage
Injections, Subcutaneous
Lichen Planus complications
Lichen Planus drug therapy
Lichen Planus immunology
Male
Middle Aged
Retrospective Studies
Scalp Dermatoses complications
Scalp Dermatoses drug therapy
Scalp Dermatoses immunology
Treatment Outcome
Alopecia Areata diagnosis
Cicatrix diagnosis
Hair Follicle pathology
Lichen Planus diagnosis
Scalp Dermatoses diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1097-6787
- Volume :
- 83
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of the American Academy of Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 31706933
- Full Text :
- https://doi.org/10.1016/j.jaad.2019.11.006