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Superagonistic CD28 protects against renal ischemia injury induced fibrosis through a regulatory T-cell expansion dependent mechanism.
- Source :
-
BMC nephrology [BMC Nephrol] 2019 Nov 09; Vol. 20 (1), pp. 407. Date of Electronic Publication: 2019 Nov 09. - Publication Year :
- 2019
- Subjects :
- Acute Kidney Injury prevention & control
Animals
Antibodies administration & dosage
CD28 Antigens immunology
Cytokines analysis
Cytokines metabolism
Disease Progression
Extracellular Matrix pathology
Fibrosis prevention & control
Interleukin-2 Receptor alpha Subunit
Ischemic Preconditioning methods
Kidney pathology
Kidney Failure, Chronic immunology
Male
Mice
Mice, Inbred C57BL
Nephritis prevention & control
Oxidative Stress
T-Lymphocytes, Regulatory cytology
Th17 Cells cytology
Time Factors
Acute Kidney Injury immunology
CD28 Antigens therapeutic use
Ischemia complications
Kidney blood supply
Renal Insufficiency, Chronic immunology
T-Lymphocytes, Regulatory immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2369
- Volume :
- 20
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC nephrology
- Publication Type :
- Academic Journal
- Accession number :
- 31706278
- Full Text :
- https://doi.org/10.1186/s12882-019-1581-x