Back to Search
Start Over
Deep radiation-induced ulcer following nasopharyngeal carcinoma: surgical management.
- Source :
-
BMJ case reports [BMJ Case Rep] 2019 Nov 05; Vol. 12 (11). Date of Electronic Publication: 2019 Nov 05. - Publication Year :
- 2019
-
Abstract
- Nasopharyngeal carcinoma (NPC), an uncommon malignancy in Western Countries and Radiotherapy, remains an effective treatment. Its side effects are classified as either immediate or late; postradiation necrosis is as an important late side effect with a strong impact on the prognosis in patients with NPC. We report the case of 65-year-old Caucasian man presenting with a deep necrotic ulcer of the nasopharynx and osteoradionecrosis of the skull base that appeared 3 months after radiotherapy for nasopharyngeal carcinoma. Conservative treatment was applied with surgical management of the ulcer. Clinical and radiological outcomes are presented. Radiotherapy remains a good treatment option with varying degrees of side effects, in particular, postradiation necrosis and ulcer. Multiple options of treatment have been described. However, the surgical management could be indicated in cases of deep ulcer with life-threatening prognosis.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Aged
Endoscopy
Humans
Male
Nasopharyngeal Carcinoma pathology
Nasopharyngeal Neoplasms pathology
Nasopharynx pathology
Osteoradionecrosis surgery
Radiation Injuries surgery
Skull Base pathology
Treatment Outcome
Ulcer surgery
Nasopharyngeal Carcinoma radiotherapy
Nasopharyngeal Neoplasms radiotherapy
Osteoradionecrosis pathology
Radiation Injuries pathology
Ulcer pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 12
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 31694827
- Full Text :
- https://doi.org/10.1136/bcr-2019-230700