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CDK4/6 Inhibitor Biomarker Research: Are We Barking Up the Wrong Tree?

Authors :
Anurag M
Haricharan S
Ellis MJ
Source :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2020 Jan 01; Vol. 26 (1), pp. 3-5. Date of Electronic Publication: 2019 Nov 05.
Publication Year :
2020

Abstract

CDK4/6 inhibitors have emerged as a significant advance for the treatment of patients with advanced estrogen receptor-positive breast cancer. However, the identification of predictive markers that optimize their use is proving harder than expected. In this commentary we advocate for unbiased discovery and a collaborative approach across trials. See related article by Finn et al., p. 110 .<br /> (©2019 American Association for Cancer Research.)

Details

Language :
English
ISSN :
1557-3265
Volume :
26
Issue :
1
Database :
MEDLINE
Journal :
Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Type :
Academic Journal
Accession number :
31690650
Full Text :
https://doi.org/10.1158/1078-0432.CCR-19-3119