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Prospectively Reallocating Sedentary Time: Associations with Cardiometabolic Health.
- Source :
-
Medicine and science in sports and exercise [Med Sci Sports Exerc] 2020 Apr; Vol. 52 (4), pp. 844-850. - Publication Year :
- 2020
-
Abstract
- Purpose: This study aimed to investigate whether prospectively reallocating time away from sedentary behavior (SB) into different physical activity intensities is associated with 12-month change to cardiometabolic health in a cohort at high risk of type 2 diabetes (T2DM).<br />Methods: Participants with known risk factors for T2DM were recruited from primary care (Leicestershire, United Kingdom) as part of the Walking Away from Type 2 Diabetes trial (n = 808). Participants were followed up at 12, 24, and 36 months. SB, light-intensity physical activity (LPA) and moderate-to-vigorous intensity physical activity (MVPA) were measured objectively by accelerometer. Postchallenge glucose, triglycerides, HDL cholesterol, systolic blood pressure, and waist circumference were analyzed individually and combined into a clustered cardiometabolic risk score (CMRS). Associations of changing SB over each consecutive 12-month period were analyzed taking account of repeated measures.<br />Results: Reallocating 30 min from SB to LPA was associated with 0.21-cm (95% confidence interval, 0.03-0.38 cm) reduction in waist circumference, 0.09-mmol·L (0.04-0.13 mmol·L) reduction in 2-h glucose, 0.02-mmol·L (0.00-0.04 mmol·L) reduction in triglycerides, and 0.02 (0.01-0.03) reduction in CMRS. Every 30-min reallocation from SB to MVPA was associated with 1.23-cm (0.68-1.79 cm) reduction in waist circumference, 0.23-mmol·L (0.10-0.36 mmol·L) reduction in 2-h glucose, 0.04-mmol·L (0.00-0.09 mmol·L) reduction in triglycerides, and 0.07 (0.04-0.11) reduction in CMRS. Reallocating 30 min from LPA into MVPA was also associated with 1.02-cm (0.43-1.60 cm) reduction in waist circumference, 0.16-mmol·L (0.02-0.30 mmol·L) reduction in 2-h glucose, and 0.05 (0.01-0.09) reduction in CMRS.<br />Conclusion: Over 12 months, reallocating time away from SB into LPA or MVPA was associated with improved cardiometabolic health in a population at risk of T2DM, with the greatest benefits observed for MVPA.
- Subjects :
- Accelerometry instrumentation
Aged
Blood Glucose metabolism
Blood Pressure
Cholesterol, HDL blood
Diabetes Mellitus, Type 2 blood
Female
Fitness Trackers
Humans
Male
Prospective Studies
Risk Factors
Triglycerides blood
Waist Circumference
Cardiorespiratory Fitness
Diabetes Mellitus, Type 2 physiopathology
Sedentary Behavior
Walking physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1530-0315
- Volume :
- 52
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Medicine and science in sports and exercise
- Publication Type :
- Academic Journal
- Accession number :
- 31688653
- Full Text :
- https://doi.org/10.1249/MSS.0000000000002204