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Preparation and characterization of core-shell type Ag@SiO 2 nanoparticles for photodynamic cancer therapy.
- Source :
-
Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2019 Dec; Vol. 28, pp. 324-329. Date of Electronic Publication: 2019 Oct 07. - Publication Year :
- 2019
-
Abstract
- With recent scientific developments, Photodynamic therapy (PDT) offers the promisie to become incorporated into the mainstream of cancer therapy. Noble metal based nano-PDT is increasing due to its advantages in the field of biomedicine. In this study, noble metal based Ag@SiO <subscript>2</subscript> core-shell nanoparticles were synthesized and to confirm the core-shell structure they were characterized by UV-vis, XRD, FTIR, TEM, and EDX. Our data confirm that core-shell type Ag@SiO <subscript>2</subscript> nanoparticles maintain its ability to kill cancer cells upon light irradiation. This shows that SiO <subscript>2</subscript> shell may not only prevent aggregation but it also may enhance the photodynamic activity of Ag nanoparticles.<br /> (Copyright © 2019 Elsevier B.V. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1873-1597
- Volume :
- 28
- Database :
- MEDLINE
- Journal :
- Photodiagnosis and photodynamic therapy
- Publication Type :
- Academic Journal
- Accession number :
- 31600577
- Full Text :
- https://doi.org/10.1016/j.pdpdt.2019.10.006