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Oral human papilloma virus infection: an overview of clinical-laboratory diagnosis and treatment.
- Source :
-
European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2019 Sep; Vol. 23 (18), pp. 8148-8157. - Publication Year :
- 2019
-
Abstract
- Objective: The aim of this review is to describe the "hot points" of current clinical governance for oral HPV comprising the use of new diagnostic molecular procedures, namely, Pyrosequencing and Next Generation Sequencing.<br />Materials and Methods: The data on oral HPV was collected through two levels of research. First for all, we used the canonical medical search engines, PubMed, and Medline, followed by the study of current commercial tools for HPV diagnosis, particularly within commercial companies involved in the molecular procedures for HPV detecting and genotyping.<br />Results: Different medical procedures are now described and used throughout the world in HPV diagnosis and treatment. However, the laboratory methods are often validated and used for genital infections, and, in these cases, data are missing in the literature as regards the clinical approach for oral lesions.<br />Conclusions: Dental care units are often the front line for a clinical evaluation of a possible HPV lesion in the oral cavity, which means that correct clinical governance could avoid a viral neoplastic progression of this disease with great advantages for the patient. In this case, the problem is due to the difficulty in lesion recognition but also and more especially the absence of correct laboratory diagnosis and subsequent treatment in the clinical course.
- Subjects :
- Carcinoma, Verrucous diagnosis
Carcinoma, Verrucous therapy
Carcinoma, Verrucous virology
Cryosurgery
Focal Epithelial Hyperplasia diagnosis
Focal Epithelial Hyperplasia therapy
Focal Epithelial Hyperplasia virology
Humans
Laser Therapy
Leukoplakia, Oral diagnosis
Leukoplakia, Oral therapy
Leukoplakia, Oral virology
Lichen Planus, Oral diagnosis
Lichen Planus, Oral therapy
Lichen Planus, Oral virology
Mouth Diseases virology
Mouth Neoplasms diagnosis
Mouth Neoplasms therapy
Mouth Neoplasms virology
Papilloma diagnosis
Papilloma therapy
Papilloma virology
Papillomaviridae genetics
Papillomavirus Infections virology
Photochemotherapy
Squamous Cell Carcinoma of Head and Neck diagnosis
Squamous Cell Carcinoma of Head and Neck therapy
Squamous Cell Carcinoma of Head and Neck virology
Warts diagnosis
Warts therapy
Warts virology
Mouth Diseases diagnosis
Mouth Diseases therapy
Papillomavirus Infections diagnosis
Papillomavirus Infections therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2284-0729
- Volume :
- 23
- Issue :
- 18
- Database :
- MEDLINE
- Journal :
- European review for medical and pharmacological sciences
- Publication Type :
- Academic Journal
- Accession number :
- 31599444
- Full Text :
- https://doi.org/10.26355/eurrev_201909_19035