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Adventures with Bruce Ames and the Ames test.
- Source :
-
Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2019 Oct; Vol. 846, pp. 403070. Date of Electronic Publication: 2019 Jul 04. - Publication Year :
- 2019
-
Abstract
- Bruce Ames has had an enormous impact on human health by developing facile methods for the identification of mutagens. This research also provided important insights into the relationship between mutagenesis and carcinogenesis. Bruce is a highly innovative and creative individual who has followed his interests across disciplines into diverse fields of inquiry. The present author had the pleasure of spending a sabbatical in the Ames lab and utilized the Ames test in multiple aspects of his research. He describes both in this honorific to Bruce on the occasion of his 90 <superscript>th</superscript> birthday.<br /> (Copyright © 2019 Elsevier B.V. All rights reserved.)
- Subjects :
- Activation, Metabolic
Animals
California
History, 20th Century
History, 21st Century
Microsomes, Liver enzymology
Molecular Structure
Mutagenesis
Mutagenicity Tests methods
Mutagens toxicity
Rats
Rats, Sprague-Dawley
Salmonella drug effects
Salmonella genetics
Biochemistry history
Genetics history
Mutagenicity Tests history
Subjects
Details
- Language :
- English
- ISSN :
- 1879-3592
- Volume :
- 846
- Database :
- MEDLINE
- Journal :
- Mutation research. Genetic toxicology and environmental mutagenesis
- Publication Type :
- Academic Journal
- Accession number :
- 31585632
- Full Text :
- https://doi.org/10.1016/j.mrgentox.2019.06.006