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Estimating population immunity to poliovirus in Jordan's high-risk areas.

Authors :
Farag NH
Wannemuehler K
Weldon W
Arbaji A
Belbaisi A
Khuri-Bulos N
Ehrhardt D
Surour MR
ElhajQasem NS
Al-Abdallat MM
Source :
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2020 Mar 03; Vol. 16 (3), pp. 548-553. Date of Electronic Publication: 2019 Nov 05.
Publication Year :
2020

Abstract

A community-based serosurvey was conducted among children ages 6-59 to assess population immunity in Jordan's high-risk areas following the Middle East polio outbreak response. The survey was a two-stage cluster-quota sample with high risk areas as the primary sampling units. High-risk areas included border and hard-to-reach areas, and areas with a high proportion of refugees, mobile communities and/or low coverage during previous immunization campaigns. Population immunity to poliovirus was high overall. In high-risk areas, Type 1 seroprevalence = 98% (95% CI = 96, 99), Type 2 = 98% (95% CI = 96, 99) and Type 3 = 96% (95% CI = 94, 98). Seroprevalence was higher in the refugee camps: Type 1 seroprevalence = 99.6% (95% CI = 97.9, 100); Type 2: 99.6% (95% CI = 97.9, 99.9), and Type 3: 100% (95% CI = 100,100). The vigilance that the Jordan Ministry of Health has placed on locating and vaccinating high-risk populations has been successful in maintaining high population immunity and averting polio outbreaks despite the influx of refugees from Syria.

Details

Language :
English
ISSN :
2164-554X
Volume :
16
Issue :
3
Database :
MEDLINE
Journal :
Human vaccines & immunotherapeutics
Publication Type :
Academic Journal
Accession number :
31584319
Full Text :
https://doi.org/10.1080/21645515.2019.1667727