Coxiella burnetii: international pathogen of mystery.

Authors :: Dragan AL
Voth DE
Source :: Microbes and infection [Microbes Infect] 2020 Apr; Vol. 22 (3), pp. 100-110. Date of Electronic Publication: 2019 Sep 28.
Publication Year :: 2020
Abstract: Coxiella burnetii is an intracellular bacterium that causes acute and chronic Q fever. This unique pathogen has been historically challenging to study due to obstacles in genetically manipulating the organism and the inability of small animal models to fully mimic human Q fever. Here, we review the current state of C. burnetii research, highlighting new approaches that allow the mechanistic study of infection in disease relevant settings.<br />Competing Interests: Declaration of Competing Interest There is no conflict of interest.<br /> (Copyright © 2019 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.)