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Portable all-fiber dual-output widely tunable light source for coherent Raman imaging.

Authors :
Brinkmann M
Fast A
Hellwig T
Pence I
Evans CL
Fallnich C
Source :
Biomedical optics express [Biomed Opt Express] 2019 Aug 05; Vol. 10 (9), pp. 4437-4449. Date of Electronic Publication: 2019 Aug 05 (Print Publication: 2019).
Publication Year :
2019

Abstract

We present a rapidly tunable dual-output all-fiber light source for coherent Raman imaging, based on a dispersively matched mode-locked laser pumping a parametric oscillator. Output pump and Stokes pulses with a maximal power of 170 and 400 mW, respectively, and equal durations of 7 ps could be generated. The tuning mechanism required no mechanical delay line, enabling all-electronic arbitrary wavelength switching across more than 2700  cm - 1 in less than 5 ms. The compact setup showed a reliable operation despite mechanical shocks of more than 25  m / s 2 and is, thus, well suited for operation in a mobile cart. Imaging mouse and human skin tissue with both the portable light source and a commercial laboratory-bound reference system yielded qualitatively equal results and verified the portable light source being well suited for coherent Raman microscopy.<br />Competing Interests: M. Brinkmann and T. Hellwig are pursuing the commercialization of the presented light source by means of the company Refined Laser Systems UG (haftungsbeschränkt), Münster, Germany (I,P,S).<br /> (Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.)

Details

Language :
English
ISSN :
2156-7085
Volume :
10
Issue :
9
Database :
MEDLINE
Journal :
Biomedical optics express
Publication Type :
Academic Journal
Accession number :
31565500
Full Text :
https://doi.org/10.1364/BOE.10.004437