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The strong case for government funding of a polypill for the secondary prevention of cardiovascular disease in New Zealand.

Authors :
Selak V
Bullen C
Arroll B
Doughty R
Doughty R
Grey C
Harwood M
Crengle S
Source :
The New Zealand medical journal [N Z Med J] 2019 Sep 20; Vol. 132 (1502), pp. 77-83. Date of Electronic Publication: 2019 Sep 20.
Publication Year :
2019

Abstract

Wald and Law, who popularised the term 'polypill' in 2003, proposed giving everyone above a certain age a polypill to reduce the burden of cardiovascular disease (CVD). A more compelling potential application, proposed in 2001 by the World Health Organization, is to use a polypill containing antiplatelet, statin and blood pressure-lowering therapy among people with established CVD, in whom the components are already indicated but in whom guideline implementation and adherence are suboptimal. This article outlines relevant international and New Zealand evidence on the likely benefits and harms of a polypill for the secondary prevention of CVD. The evidence indicates that the benefits are likely to outweigh the harms, particularly given the persistence of substantial treatment gaps and inequities in the management of and outcomes in CVD. The time is long overdue for the polypill to be funded for the secondary prevention of CVD.<br />Competing Interests: Nil.

Details

Language :
English
ISSN :
1175-8716
Volume :
132
Issue :
1502
Database :
MEDLINE
Journal :
The New Zealand medical journal
Publication Type :
Academic Journal
Accession number :
31563929