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The strong case for government funding of a polypill for the secondary prevention of cardiovascular disease in New Zealand.
- Source :
-
The New Zealand medical journal [N Z Med J] 2019 Sep 20; Vol. 132 (1502), pp. 77-83. Date of Electronic Publication: 2019 Sep 20. - Publication Year :
- 2019
-
Abstract
- Wald and Law, who popularised the term 'polypill' in 2003, proposed giving everyone above a certain age a polypill to reduce the burden of cardiovascular disease (CVD). A more compelling potential application, proposed in 2001 by the World Health Organization, is to use a polypill containing antiplatelet, statin and blood pressure-lowering therapy among people with established CVD, in whom the components are already indicated but in whom guideline implementation and adherence are suboptimal. This article outlines relevant international and New Zealand evidence on the likely benefits and harms of a polypill for the secondary prevention of CVD. The evidence indicates that the benefits are likely to outweigh the harms, particularly given the persistence of substantial treatment gaps and inequities in the management of and outcomes in CVD. The time is long overdue for the polypill to be funded for the secondary prevention of CVD.<br />Competing Interests: Nil.
- Subjects :
- Drug Combinations
Government Regulation
Humans
New Zealand epidemiology
Program Evaluation
Risk Assessment
Tablets
Antihypertensive Agents pharmacology
Cardiovascular Diseases drug therapy
Cardiovascular Diseases epidemiology
Cardiovascular Diseases prevention & control
Hydroxymethylglutaryl-CoA Reductase Inhibitors pharmacology
Platelet Aggregation Inhibitors pharmacology
Secondary Prevention economics
Secondary Prevention methods
Secondary Prevention organization & administration
Subjects
Details
- Language :
- English
- ISSN :
- 1175-8716
- Volume :
- 132
- Issue :
- 1502
- Database :
- MEDLINE
- Journal :
- The New Zealand medical journal
- Publication Type :
- Academic Journal
- Accession number :
- 31563929