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Physician characteristics associated with treatment initiation patterns in idiopathic pulmonary fibrosis.
- Source :
-
Chronic respiratory disease [Chron Respir Dis] 2019 Jan-Dec; Vol. 16, pp. 1479973119879678. - Publication Year :
- 2019
-
Abstract
- Pirfenidone and nintedanib are oral antifibrotic agents approved for the treatment of idiopathic pulmonary fibrosis (IPF). Real-world data on factors that influence IPF treatment decisions are limited. Physician characteristics associated with antifibrotic therapy initiation following an IPF diagnosis were examined in a sample of US pulmonologists. An online, self-administered survey was fielded to pulmonologists between April 10, 2017, and May 17, 2017. Pulmonologists were included if they spent >20% of their time in direct patient care and had ≥5 patients with IPF receiving antifibrotics. Participants answered questions regarding timing and reasons for considering the initiation of antifibrotic therapy after an IPF diagnosis. A total of 169 pulmonologists participated. The majority (81.7%) considered initiating antifibrotic therapy immediately after IPF diagnosis all or most of the time (immediate group), while 18.3% considered it only some of the time or not at all (delayed group). Pulmonologists in the immediate group were more likely to work in private practice (26.1%), have a greater mean percentage of patients receiving antifibrotic therapy (60.8%), and decide to initiate treatment themselves (31.2%) versus those in the delayed group (16.1%, 30.5%, and 16.1%, respectively). Most pulmonologists consider initiating antifibrotic treatment immediately after establishing an IPF diagnosis all or most of the time versus using a "watch-and-wait" approach. Distinguishing characteristics between pulmonologists in the immediate group versus the delayed group included practice setting, percentage of patients receiving antifibrotic therapy, and the decision-making dynamics between the patient and the pulmonologist.
- Subjects :
- Antineoplastic Agents administration & dosage
Clinical Decision-Making
Humans
Indoles administration & dosage
Patient Participation
Private Practice statistics & numerical data
Pyridones administration & dosage
Surveys and Questionnaires
Time Factors
United States
Watchful Waiting statistics & numerical data
Antineoplastic Agents therapeutic use
Idiopathic Pulmonary Fibrosis drug therapy
Indoles therapeutic use
Practice Patterns, Physicians'
Pulmonary Medicine statistics & numerical data
Pyridones therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1479-9731
- Volume :
- 16
- Database :
- MEDLINE
- Journal :
- Chronic respiratory disease
- Publication Type :
- Academic Journal
- Accession number :
- 31558049
- Full Text :
- https://doi.org/10.1177/1479973119879678