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Benzocaine: Review on a Drug with Unfold Potential.
- Source :
-
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2020; Vol. 20 (1), pp. 3-11. - Publication Year :
- 2020
-
Abstract
- Benzocaine is well-known for its role as an anesthetic agent and largely used in oral ulcers, ear pain and dental complications. Along with lidocaine and other local anesthetics, benzocaine has marked it as an anesthetic agent in surgical procedures and as Na+ channels blocker, as well. Analogues of benzocaine have been found to possess biological potentials including antibacterial, antifungal and anti-cancer. Some derivatives were found to have conspicuous action against tuberculosis. The current review focuses to explore the century-long potential of the molecule and its analogs that have appeared in the literature. Furthermore, highlighting the biological potential of benzocaine and its analogues shall open-up new dimensions of future research to design more potent analogues.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
- Subjects :
- Anesthetics, Local therapeutic use
Animals
Anti-Infective Agents chemistry
Anti-Infective Agents pharmacology
Anti-Infective Agents therapeutic use
Antineoplastic Agents chemistry
Antineoplastic Agents pharmacology
Antineoplastic Agents therapeutic use
Benzocaine therapeutic use
Drug Discovery methods
Humans
Anesthetics, Local chemistry
Anesthetics, Local pharmacology
Benzocaine analogs & derivatives
Benzocaine pharmacology
Drug Development methods
Subjects
Details
- Language :
- English
- ISSN :
- 1875-5607
- Volume :
- 20
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Mini reviews in medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 31518221
- Full Text :
- https://doi.org/10.2174/1389557519666190913145423