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Benzocaine: Review on a Drug with Unfold Potential.

Authors :
Khair-Ul-Bariyah S
Arshad M
Ali M
Din MI
Sharif A
Ahmed E
Source :
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2020; Vol. 20 (1), pp. 3-11.
Publication Year :
2020

Abstract

Benzocaine is well-known for its role as an anesthetic agent and largely used in oral ulcers, ear pain and dental complications. Along with lidocaine and other local anesthetics, benzocaine has marked it as an anesthetic agent in surgical procedures and as Na+ channels blocker, as well. Analogues of benzocaine have been found to possess biological potentials including antibacterial, antifungal and anti-cancer. Some derivatives were found to have conspicuous action against tuberculosis. The current review focuses to explore the century-long potential of the molecule and its analogs that have appeared in the literature. Furthermore, highlighting the biological potential of benzocaine and its analogues shall open-up new dimensions of future research to design more potent analogues.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Details

Language :
English
ISSN :
1875-5607
Volume :
20
Issue :
1
Database :
MEDLINE
Journal :
Mini reviews in medicinal chemistry
Publication Type :
Academic Journal
Accession number :
31518221
Full Text :
https://doi.org/10.2174/1389557519666190913145423