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Tandem Wittig Reaction-Ring Contraction of Cyclobutanes: A Route to Functionalized Cyclopropanecarbaldehydes.

Authors :
Cuccu F
Serusi L
Luridiana A
Secci F
Caboni P
Aitken DJ
Frongia A
Source :
Organic letters [Org Lett] 2019 Oct 04; Vol. 21 (19), pp. 7755-7758. Date of Electronic Publication: 2019 Sep 13.
Publication Year :
2019

Abstract

An original tandem reaction consisting of a Wittig reaction-ring contraction process between α-hydroxycyclobutanone and phosphonium ylides has been developed. Highly functionalized cyclopropanecarbaldehydes are obtained in good to high yield.

Details

Language :
English
ISSN :
1523-7052
Volume :
21
Issue :
19
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
31518144
Full Text :
https://doi.org/10.1021/acs.orglett.9b02690