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Regenerative treatment with umbilical cord mesenchymal stem cells from Wharton's jelly in chronic ulcer caused by dermolipectomy.

Authors :
Mejía-Barradas CM
Cázares-Montañez JE
Guerra-Márquez Á
Hernández-Chávez VG
Cáceres-Cortés JR
Gutiérrez-Iglesias G
Source :
Cirugia y cirujanos [Cir Cir] 2019; Vol. 87 (S1), pp. 8-16.
Publication Year :
2019

Abstract

Background: Procedures to remove adiposities and skin, such as dermolipectomy, can develop wounds that are difficult to heal by conventional therapies. Mesenchymal stem cells are indicated as potential candidates for regenerative therapy in wounds, due to their multipotentiality, low immunogenicity, modulating capacity of inflammation and tissue modeling processes.<br />Case Report: Patient with dehiscent chronic ulcer secondary to dermolipectomy, who received cutaneous treatment with mesenchymal stem cells. The therapy induced scar formation and neovascularization, as well as the decrease of infiltrated leukocytes and proinflammatory cytokines. Mesenchymal cells are proposed as an interesting alternative for the treatment of postoperative lesions.<br /> (Copyright: © 2019 Permanyer.)

Details

Language :
English
ISSN :
2444-054X
Volume :
87
Issue :
S1
Database :
MEDLINE
Journal :
Cirugia y cirujanos
Publication Type :
Academic Journal
Accession number :
31501623
Full Text :
https://doi.org/10.24875/CIRU.18000515