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Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis.
- Source :
-
Scientific reports [Sci Rep] 2019 Sep 03; Vol. 9 (1), pp. 12678. Date of Electronic Publication: 2019 Sep 03. - Publication Year :
- 2019
-
Abstract
- The purpose of this study is to evaluate the prognostic factors associated with visual outcomes in the salvageable eyes with posttraumatic endophthalmitis. We retrospectively reviewed the medical records of all patients diagnosed with posttraumatic endophthalmitis in our hospital between 2008 and 2015. The following information was collected: age, sex, etiology, past medical history, clinical manifestations, wound location, microbiology, blood leukocyte counts, types of interventions, initial visual acuities and final visual acuities. Univariate and multivariate analyses were used to explore the factors associated with final best-corrected visual acuity. In total, 98 eyes of 98 patients were included in our study. Fifty-seven eyes underwent vitrectomy, 27 of them had silicone oil tamponade, 38 eyes received intravitreal ceftazidime only and 3 eyes received intracameral ceftazidime. In univariate analysis, poor initial visual acuity, presence of intraocular foreign body, number of intravitreal injections, retinal detachment and Zone 3 injury were associated with poor visual outcome. In multivariable analysis, poor initial visual acuity, presence of intraocular foreign body and number of intravitreal injections were independently associated with poor visual outcome. The silicone oil group had fewer repeated intravitreal injections than the group without oil tamponade. We concluded that the visual outcome of salvageable eyes with posttraumatic endophthalmitis is associated with initial visual acuity, presence of intraocular foreign body and number of intravitreal antibiotic injections.
- Subjects :
- Adolescent
Adult
Aged
Anti-Bacterial Agents pharmacology
Anti-Bacterial Agents therapeutic use
Ceftazidime pharmacology
Ceftazidime therapeutic use
Child
Child, Preschool
Endophthalmitis drug therapy
Endophthalmitis microbiology
Female
Humans
Male
Middle Aged
Prognosis
Retinal Detachment etiology
Retinal Detachment pathology
Retrospective Studies
Silicone Oils therapeutic use
Staphylococcus epidermidis drug effects
Staphylococcus epidermidis isolation & purification
Vitrectomy
Young Adult
Endophthalmitis diagnosis
Visual Acuity
Subjects
Details
- Language :
- English
- ISSN :
- 2045-2322
- Volume :
- 9
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Scientific reports
- Publication Type :
- Academic Journal
- Accession number :
- 31481709
- Full Text :
- https://doi.org/10.1038/s41598-019-49117-w