Puzzling mRNA: Alternative splicing fine-tunes specificity and function.

Authors :: Häfner SJ
Source :: Biomedical journal [Biomed J] 2019 Jun; Vol. 42 (3), pp. 137-140. Date of Electronic Publication: 2019 Jul 25.
Publication Year :: 2019
Abstract: In this issue of the Biomedical Journal we discover how alternative splicing might modulate the cell-type specificity and exact function of a ubiquitous purinergic receptor and how the beta blocker propanolol can contribute to breast cancer therapy. Moreover, we learn which culture conditions generate the best vascularisation of tissue engineered bone and which are the clinical features of acute necrotising encephalopathy in adults. Other studies reveal, how laser irradiation can fix fractured all-ceramic dental restorations in situ, and finally that nuclear magnetic resonance holds great potential for the rapid detection of pathogens.<br /> (Copyright © 2019 Chang Gung University. Published by Elsevier B.V. All rights reserved.)