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Unusual Bone Lesions with Osteonecrosis Mimicking Bone Metastasis of Squamous Cell Carcinoma in Recessive Dystrophic Epidermolysis Bullosa.
- Source :
-
Acta dermato-venereologica [Acta Derm Venereol] 2019 Nov 01; Vol. 99 (12), pp. 1166-1169. - Publication Year :
- 2019
-
Abstract
- Some bone lesions are reported to mimic bone metastasis on imaging tests. Herein, we report a case of a 55-year-old Japanese man who presented with a skin tumor on the left lower extremity. He also had a history of recurrent generalized cutaneous blister and erosion formation since childhood. His skin lesions were diagnosed as cutaneous squamous cell carcinoma complicated by recessive dystrophic epidermolysis bullosa. Magnetic resonance imaging of the left lower extremity detected multiple focal bone lesions mimicking bone metastases in the left femur and tibia. However, bone biopsy revealed that the bone lesions were osteonecrosis without tumor cells. We suggest that cancer-induced osteonecrosis should be included in the differential diagnosis of bone lesions suspected of being metastases on magnetic resonance imaging.
- Subjects :
- Biopsy
Bone Neoplasms secondary
Carcinoma, Squamous Cell secondary
Diagnosis, Differential
Epidermolysis Bullosa Dystrophica pathology
Femoral Neoplasms secondary
Humans
Male
Middle Aged
Osteonecrosis pathology
Predictive Value of Tests
Skin Neoplasms pathology
Tibia pathology
Bone Neoplasms diagnostic imaging
Carcinoma, Squamous Cell diagnostic imaging
Epidermolysis Bullosa Dystrophica diagnostic imaging
Femoral Neoplasms diagnostic imaging
Magnetic Resonance Imaging
Osteonecrosis diagnostic imaging
Skin Neoplasms diagnostic imaging
Tibia diagnostic imaging
Subjects
Details
- Language :
- English
- ISSN :
- 1651-2057
- Volume :
- 99
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Acta dermato-venereologica
- Publication Type :
- Report
- Accession number :
- 31453627
- Full Text :
- https://doi.org/10.2340/00015555-3303