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Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup.
- Source :
-
Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2019 Nov; Vol. 34 (11), pp. 2427-2448. Date of Electronic Publication: 2019 Aug 24. - Publication Year :
- 2019
-
Abstract
- Background: Intentional or unintentional ingestions among children and adolescents are common. There are a number of ingestions amenable to renal replacement therapy (RRT).<br />Methods: We systematically searched PubMed/Medline, Embase, and Cochrane databases for literature regarding drugs/intoxicants and treatment with RRT in pediatric populations. Two experts from the PCRRT (Pediatric Continuous Renal Replacement Therapy) workgroup assessed titles, abstracts, and full-text articles for extraction of data. The data from the literature search was shared with the PCRRT workgroup and two expert toxicologists, and expert panel recommendations were developed.<br />Results and Conclusions: We have presented the recommendations concerning the use of RRTs for treatment of intoxications with toxic alcohols, lithium, vancomycin, theophylline, barbiturates, metformin, carbamazepine, methotrexate, phenytoin, acetaminophen, salicylates, valproic acid, and aminoglycosides.
- Subjects :
- Acute Kidney Injury diagnosis
Acute Kidney Injury etiology
Adolescent
Child
Child, Preschool
Consensus Development Conferences as Topic
Female
Humans
Infant
Male
Nephrology standards
Poisoning diagnosis
Poisoning etiology
Young Adult
Acute Kidney Injury therapy
Consensus
Poisoning therapy
Practice Guidelines as Topic
Renal Replacement Therapy standards
Subjects
Details
- Language :
- English
- ISSN :
- 1432-198X
- Volume :
- 34
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Pediatric nephrology (Berlin, Germany)
- Publication Type :
- Academic Journal
- Accession number :
- 31446483
- Full Text :
- https://doi.org/10.1007/s00467-019-04319-2