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Neural processing critical for distinguishing between speech sounds.
- Source :
-
Brain and language [Brain Lang] 2019 Oct; Vol. 197, pp. 104677. Date of Electronic Publication: 2019 Aug 20. - Publication Year :
- 2019
-
Abstract
- We aimed to identify neural regions where ischemia acutely after stroke is associated with impairment in phoneme discrimination, and to determine whether such deficits are associated with impairment of spoken word comprehension. We evaluated 33 patients within 48 h of left hemisphere ischemic stroke onset with tests of phoneme discrimination and word-picture matching. We identified Pearson correlations between accuracy in phoneme discrimination and accuracy of word comprehension and identified areas where the percentage of infarcted tissue was associated with severity of phoneme discrimination deficit. We found that 54% had deficits in phoneme discrimination relative to healthy controls. Accuracy in phoneme discrimination correlated with accuracy on word comprehension tests. Damage to left intraparietal sulcus and hypoperfusion and/or infarct of left superior temporal gyrus were associated with phoneme discrimination deficits acutely, although patients with these lesions showed improvement or resolution of the deficit by six months.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)
- Subjects :
- Brain pathology
Brain physiopathology
Case-Control Studies
Female
Humans
Male
Middle Aged
Parietal Lobe pathology
Parietal Lobe physiopathology
Stroke pathology
Stroke physiopathology
Temporal Lobe pathology
Temporal Lobe physiopathology
Brain cytology
Brain physiology
Comprehension physiology
Phonetics
Speech Perception physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1090-2155
- Volume :
- 197
- Database :
- MEDLINE
- Journal :
- Brain and language
- Publication Type :
- Academic Journal
- Accession number :
- 31442633
- Full Text :
- https://doi.org/10.1016/j.bandl.2019.104677