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Focused ultrasound resolves persistent radiosurgery related change in a patient with tremor.

Focused ultrasound resolves persistent radiosurgery related change in a patient with tremor.

Authors :
Mazerolle EL
Seasons GM
Warwaruk-Rogers R
Romo P
Nordal R
Sevick RJ
Martino D
Pichardo S
Kiss ZHT
Pike GB
Source :
Radiology case reports [Radiol Case Rep] 2019 Aug 06; Vol. 14 (10), pp. 1233-1236. Date of Electronic Publication: 2019 Aug 06 (Print Publication: 2019).
Publication Year :
2019

Abstract

We report on a patient who underwent magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy to treat tremor 3 years after a stereotactic radiosurgery (SRS) thalamotomy. The SRS produced only limited and transient improvements and was associated with a persistent hyperintensity on T2-FLAIR MR images. The MRgFUS thalamotomy was successful, with tremor improvement at 3 months, no adverse effects, and radiological appearance of the MRgFUS lesion similar to other patients undergoing this therapy. We also observed that the SRS-related T2-FLAIR hyperintensity had increased signal intensity 1 day post-MRgFUS, but appeared completely resolved 3 months post-MRgFUS. In conclusion, the case demonstrates that MRgFUS thalamotomy may effectively control tremor in patients with a history of SRS thalamotomy. We also speculate on the potential mechanisms of the apparent resolution of radiation-related change, and discuss possible applications of MRgFUS to reduce persistent SRS-related inflammation.

Details

Language :
English
ISSN :
1930-0433
Volume :
14
Issue :
10
Database :
MEDLINE
Journal :
Radiology case reports
Publication Type :
Report
Accession number :
31440321
Full Text :
https://doi.org/10.1016/j.radcr.2019.07.010