Sofosbuvir Add-on to Ribavirin Treatment for Chronic Hepatitis E Virus Infection in Solid Organ Transplant Recipients Does Not Result in Sustained Virological Response.

Authors :: van Wezel EM
de Bruijne J
Damman K
Bijmolen M
van den Berg AP
Verschuuren EAM
Ruigrok GA
Riezebos-Brilman A
Knoester M
Source :: Open forum infectious diseases [Open Forum Infect Dis] 2019 Aug 01; Vol. 6 (8).
Publication Year :: 2019
Abstract: Ribavirin is effective for treating immunocompromised patients with chronic hepatitis E virus infection. However, ribavirin treatment is not always successful. We describe 3 solid organ transplant recipients treated with sofosbuvir and ribavirin after failing ribavirin monotherapy. Complete elimination of hepatitis E virus could not be achieved.<br /> (© The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)

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