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Anti-biofilm activity of quinazoline derivatives against Mycobacterium smegmatis .
- Source :
-
MedChemComm [Medchemcomm] 2019 May 23; Vol. 10 (7), pp. 1177-1179. Date of Electronic Publication: 2019 May 23 (Print Publication: 2019). - Publication Year :
- 2019
-
Abstract
- Bacteria employ a number of mechanisms to resist the effects of antibiotics, including the formation of biofilms. We explored the anti-biofilm capabilities of a library of compounds based upon a 2-aminoquinazoline (2-AQ) scaffold against Mycobacterium smegmatis . This study resulted in the identification of 2-AQ derivatives with biofilm inhibition activity against M. smegmatis .
Details
- Language :
- English
- ISSN :
- 2040-2511
- Volume :
- 10
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- MedChemComm
- Publication Type :
- Academic Journal
- Accession number :
- 31391891
- Full Text :
- https://doi.org/10.1039/c9md00156e