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Sleep Pharmacogenetics: The Promise of Precision Medicine.

Authors :
Krystal AD
Prather AA
Source :
Sleep medicine clinics [Sleep Med Clin] 2019 Sep; Vol. 14 (3), pp. 317-331. Date of Electronic Publication: 2019 Jun 14.
Publication Year :
2019

Abstract

Pharmacogenetics is the branch of personalized medicine concerned with the variability in drug response occurring because of heredity. Advances in genetics research, and decreasing costs of gene sequencing, are promoting tremendous growth in pharmacogenetics in all areas of medicine, including sleep medicine. This article reviews the body of research indicating that there are genetic variations that affect the therapeutic actions and adverse effects of agents used for the treatment of sleep disorders to show the potential of pharmacogenetics to improve the clinical practice of sleep medicine.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1556-4088
Volume :
14
Issue :
3
Database :
MEDLINE
Journal :
Sleep medicine clinics
Publication Type :
Academic Journal
Accession number :
31375201
Full Text :
https://doi.org/10.1016/j.jsmc.2019.05.003