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Mood and suicidality outcomes 3-11 years following pediatric anxiety disorder treatment.
- Source :
-
Depression and anxiety [Depress Anxiety] 2019 Oct; Vol. 36 (10), pp. 930-940. Date of Electronic Publication: 2019 Jul 29. - Publication Year :
- 2019
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Abstract
- Background: Youth anxiety interventions have potential to reduce risk for depression and suicidality.<br />Methods: This naturalistic follow-up of the multi-site, comparative treatment trial, inking and behavior, and depressive symptoms 3-11 years (mean 6.25 years) following 12-week evidence-based youth anxiety treatment. Participants (N = 319; 10-26 years, mean 17 years) completed semiannual questionnaires and annual diagnostic interviews for 4 years.<br />Results: One-fifth (20.4%) of the sample met DSM-IV criteria for a mood disorder, 32.1% endorsed suicidal ideation, and 8.2% reported suicidal behavior. Latent class growth analysis yielded two linear trajectories of depressive symptoms, and 85% of the sample demonstrated a persistent low-symptom course over seven assessments. Child/Adolescent Anxiety Multimodal Study (CAMS) 12-week treatment outcome (positive response, remission) and treatment condition (cognitive behavior therapy [CBT], medication, CBT + medication, pill placebo) were not associated with subsequent mood disorder or suicidal thinking. CAMS remission predicted absence of suicidal behavior, and treatment response and remission predicted low depressive symptom trajectory. Greater baseline self-reported depressive symptoms predicted all long-term mood outcomes, and more negative life events predicted subsequent mood disorder, depressive symptom trajectory, and suicidal ideation.<br />Conclusions: Effective early treatment of youth anxiety, including CBT, medication, or CBT + medication, reduces risk for subsequent chronic depressive symptoms and suicidal behavior. Attention to (sub)clinical depressive symptoms and management of negative life events may reduce odds of developing a mood disorder, chronic depressive symptoms, and suicidality. Findings contribute to evidence that early intervention for a primary disorder can serve as secondary prevention.<br /> (© 2019 Wiley Periodicals, Inc.)
- Subjects :
- Adolescent
Adult
Anxiety complications
Anxiety psychology
Anxiety Disorders complications
Anxiety Disorders psychology
Child
Cognitive Behavioral Therapy
Depression complications
Depression psychology
Depression therapy
Diagnostic and Statistical Manual of Mental Disorders
Female
Follow-Up Studies
Humans
Male
Risk Factors
Self Report
Suicidal Ideation
Surveys and Questionnaires
Time Factors
Treatment Outcome
Young Adult
Suicide Prevention
Affect
Anxiety therapy
Anxiety Disorders therapy
Suicide psychology
Suicide statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1520-6394
- Volume :
- 36
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Depression and anxiety
- Publication Type :
- Academic Journal
- Accession number :
- 31356713
- Full Text :
- https://doi.org/10.1002/da.22944