Isolated growth hormone deficiency presenting with recurrent hypoglycaemia in a toddler.

Authors :: Boro H
Goyal A
Khadgawat R
Source :: BMJ case reports [BMJ Case Rep] 2019 Jul 27; Vol. 12 (7). Date of Electronic Publication: 2019 Jul 27.
Publication Year :: 2019
Abstract: Hypoglycaemia in infants and children is caused by a number of endocrine and metabolic defects, some of which are unique to this age group. Growth hormone deficiency (GHD) has been rarely reported as a cause of recurrent fasting hypoglycaemia in children. An 18-month-old male child presented to us for evaluation of neuroglycopenic symptoms caused by recurrent episodes of fasting hypoglycaemia. Laboratory evaluation revealed ketotic hypoinsulinaemic hypoglycaemia. The child was diagnosed to have GHD on the basis of two failed stimulation tests. A detailed work-up for metabolic and other hormonal causes of hypoglycaemia was negative. We present the case for its rarity and to highlight the importance of a detailed metabolic and hormonal assessment in evaluation of childhood hypoglycaemia.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.)

Subjects :: Directive Counseling
Dwarfism, Pituitary complications
Dwarfism, Pituitary physiopathology
Humans
Hypoglycemia etiology
Hypoglycemia physiopathology
Hypoglycemia therapy
Infant
Male
Recurrence
Treatment Outcome
Dietary Carbohydrates therapeutic use
Dwarfism, Pituitary diagnosis
Fasting adverse effects
Human Growth Hormone therapeutic use
Hypoglycemia diagnosis

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