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CAR T-cell Therapy Yields Durable Remissions in FL.

Source :
Cancer discovery [Cancer Discov] 2019 Sep; Vol. 9 (9), pp. OF4. Date of Electronic Publication: 2019 Jul 22.
Publication Year :
2019

Abstract

In a phase I/II study, chimeric antigen receptor T cells produced complete remissions in 88% of patients with refractory or relapsed follicular lymphoma, all of whom remained in remission after a median of 2 years of follow-up. The treatment induced cytokine release syndrome and neurotoxicity in 50% of patients, but none developed side effects more severe than grade 2.<br /> (©2019 American Association for Cancer Research.)

Details

Language :
English
ISSN :
2159-8290
Volume :
9
Issue :
9
Database :
MEDLINE
Journal :
Cancer discovery
Publication Type :
Periodical
Accession number :
31332022
Full Text :
https://doi.org/10.1158/2159-8290.CD-NB2019-082