Cross-cultural Adaptation and Multi-centric Validation of the Motor Function Measure Chinese Version (MFM-32-CN) for Patients with Neuromuscular Diseases.

Aim: This study aims to produce a Chinese translation and adaptation of the MFM-32 and examine its measurement parametric properties in Chinese population with neuromuscular diseases. Methods: The MFM-32-CN was validated by testing reliability, internal consistency, and construct validity. Results: The Interrater and intrarater reliability of MFM-32-CN were moderate to excellent for each item, and excellent for the total score and the subscores. The internal consistency was high for the global scale and subscales. The total score was strongly related to the VAS and Vignos grade, and to a lesser degree to the Brooke grade. The discriminant validity was good. Conclusion: MFM-32-CN has satisfactory reliability, internal consistency, convergent validity and discriminant validity in youngsters with DMD, and good psychometric properties have also been observed for the whole population tested combining different NMD groups, but future study with a larger number of participants in each disease group is needed to confirm the present results.