Back to Search Start Over

Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety.

Authors :
Szőke K
Czompa A
Lekli I
Szabados-Fürjesi P
Herczeg M
Csávás M
Borbás A
Herczegh P
Tósaki Á
Source :
Data in brief [Data Brief] 2019 Jun 12; Vol. 25, pp. 104146. Date of Electronic Publication: 2019 Jun 12 (Print Publication: 2019).
Publication Year :
2019

Abstract

Herein <superscript>1</superscript> H and <superscript>13</superscript> C NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the linsidomine-aspirin hybrid in oxidation reactions. This data article also concerns miscellaneous myocardial parameters of isolated rat hearts as a complementation of the tables shown in the paper entitled "A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety" Szoke et al., 2019. Column tables represent data of aorta flow, aortic pressure, derivated aortic pressure and cardiac output.

Details

Language :
English
ISSN :
2352-3409
Volume :
25
Database :
MEDLINE
Journal :
Data in brief
Publication Type :
Academic Journal
Accession number :
31297426
Full Text :
https://doi.org/10.1016/j.dib.2019.104146