Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir 1 .

Authors :: Mishin VP
Patel MC
Chesnokov A
De La Cruz J
Nguyen HT
Lollis L
Hodges E
Jang Y
Barnes J
Uyeki T
Davis CT
Wentworth DE
Gubareva LV
Source :: Emerging infectious diseases [Emerg Infect Dis] 2019 Oct; Vol. 25 (10), pp. 1969-1972. Date of Electronic Publication: 2019 Oct 17.
Publication Year :: 2019
Abstract: Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors.