Back to Search
Start Over
Aristololactam alkaloids from the roots of Dasymaschalon rostratum .
- Source :
-
Natural product research [Nat Prod Res] 2021 Apr; Vol. 35 (7), pp. 1084-1089. Date of Electronic Publication: 2019 Jul 09. - Publication Year :
- 2021
-
Abstract
- A novel aristololactam alkaloid, dasymalactam A ( 1 ), together with nine known analogues ( 2-10 ), were isolated from the roots of Dasymaschalon rostratum . Their structures were elucidated by IR, NMR and MS spectrums and comparisons with data reported in the literature. All compounds demonstrated weak cytotoxicity against Hela, MCF-7, A-549, MGC-803, and COLO-205 human cancer cell lines.
- Subjects :
- Alkaloids chemistry
Alkaloids pharmacology
Aristolochic Acids chemistry
Aristolochic Acids pharmacology
Cell Line, Tumor
Doxorubicin pharmacology
Humans
Inhibitory Concentration 50
Alkaloids isolation & purification
Annonaceae chemistry
Aristolochic Acids isolation & purification
Plant Roots chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1478-6427
- Volume :
- 35
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 31286798
- Full Text :
- https://doi.org/10.1080/14786419.2019.1638384