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Probiotic Ingestion, Obesity, and Metabolic-Related Disorders: Results from NHANES, 1999-2014.
- Source :
-
Nutrients [Nutrients] 2019 Jun 28; Vol. 11 (7). Date of Electronic Publication: 2019 Jun 28. - Publication Year :
- 2019
-
Abstract
- Gut microbiota dysbiosis has been recognized as having key importance in obesity- and metabolic-related diseases. Although there is increasing evidence of the potential benefits induced by probiotics in metabolic disturbances, there is a lack of large cross-sectional studies to assess population-based prevalence of probiotic intake and metabolic diseases. Our aim was to evaluate the association of probiotic ingestion with obesity, type 2 diabetes, hypertension, and dyslipidemia. A cross-sectional study was designed using data from the National Health and Nutrition Examination Survey (NHANES), 1999-2014. Probiotic ingestion was considered when a subject reported consumption of yogurt or a probiotic supplement during the 24-hour dietary recall or during the Dietary Supplement Use 30-Day questionnaire. We included 38,802 adults and 13.1% reported probiotic ingestion. The prevalence of obesity and hypertension was lower in the probiotic group (obesity-adjusted Odds Ratio (OR): 0.84, 95% CI 0.76-0.92, p < 0.001; hypertension-adjusted OR: 0.79, 95% CI 0.71-0.88, p < 0.001). Accordingly, even after analytic adjustments, body mass index (BMI) was significantly lower in the probiotic group, as were systolic and diastolic blood pressure and triglycerides; high-density lipoprotein (HDL) was significantly higher in the probiotic group for the adjusted model. In this large-scale study, ingestion of probiotic supplements or yogurt was associated with a lower prevalence of obesity and hypertension.<br />Competing Interests: The authors declare no conflict of interest.
- Subjects :
- Adult
Cross-Sectional Studies
Diabetes Mellitus, Type 2 diagnosis
Diabetes Mellitus, Type 2 epidemiology
Diabetes Mellitus, Type 2 microbiology
Dysbiosis
Dyslipidemias diagnosis
Dyslipidemias epidemiology
Dyslipidemias microbiology
Female
Humans
Hypertension diagnosis
Hypertension epidemiology
Hypertension microbiology
Male
Middle Aged
Obesity diagnosis
Obesity epidemiology
Obesity microbiology
Prevalence
Protective Factors
Risk Assessment
Risk Factors
United States epidemiology
Diabetes Mellitus, Type 2 prevention & control
Dyslipidemias prevention & control
Gastrointestinal Microbiome
Gastrointestinal Tract microbiology
Hypertension prevention & control
Obesity prevention & control
Probiotics administration & dosage
Yogurt microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 2072-6643
- Volume :
- 11
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Nutrients
- Publication Type :
- Academic Journal
- Accession number :
- 31261830
- Full Text :
- https://doi.org/10.3390/nu11071482