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Glyburide, a NLRP3 Inhibitor, Decreases Inflammatory Response and Is a Candidate to Reduce Pathology in Leishmania braziliensis Infection.
- Source :
-
The Journal of investigative dermatology [J Invest Dermatol] 2020 Jan; Vol. 140 (1), pp. 246-249.e2. Date of Electronic Publication: 2019 Jun 25. - Publication Year :
- 2020
- Subjects :
- Biopsy
Brazil
Cells, Cultured
Cytokines metabolism
Endemic Diseases
Humans
Inflammation Mediators metabolism
Leishmaniasis, Cutaneous transmission
Skin drug effects
Glyburide pharmacology
Hypoglycemic Agents pharmacology
Leishmania braziliensis physiology
Leishmaniasis, Cutaneous drug therapy
Macrophages immunology
NLR Family, Pyrin Domain-Containing 3 Protein antagonists & inhibitors
Skin pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1523-1747
- Volume :
- 140
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Journal of investigative dermatology
- Publication Type :
- Report
- Accession number :
- 31252034
- Full Text :
- https://doi.org/10.1016/j.jid.2019.05.025