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Bone metastases from a 1p/19q codeleted and IDH1-mutant anaplastic oligodendroglioma: a case report.

Authors :
Burgy M
Chenard MP
Noël G
Bourahla K
Schott R
Source :
Journal of medical case reports [J Med Case Rep] 2019 Jun 28; Vol. 13 (1), pp. 202. Date of Electronic Publication: 2019 Jun 28.
Publication Year :
2019

Abstract

Background: Oligodendroglioma is a rare type of primary brain tumor which, like other malignant gliomas, metastasizes very rarely even when in high-grade form.<br />Case Report: A 36-year-old white man diagnosed 29 months previously as having 1p/19q codeleted anaplastic oligodendroglioma presented bilateral cruralgia and lower limb motor deficits. A computed tomography scan showed multiple osteoblastic bone lesions. The presence of oligodendroglial cells was revealed by bone marrow biopsy and confirmed by immunohistochemical analyses. A positon emission tomography-computed tomography scan confirmed the exclusive involvement of bones.<br />Conclusion: This case joins less than 20 other reported cases of oligodendroglioma bone marrow metastasis, and is one of only a handful of cases of diffuse bone metastases beyond the axial skeleton. To the best of our knowledge, the early relapse of 1p/19q codeleted anaplastic oligodendroglioma with this distribution of metastases has never been described in the literature.

Details

Language :
English
ISSN :
1752-1947
Volume :
13
Issue :
1
Database :
MEDLINE
Journal :
Journal of medical case reports
Publication Type :
Academic Journal
Accession number :
31248444
Full Text :
https://doi.org/10.1186/s13256-019-2061-4