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Management of an aggressive giant cell granuloma of the mandible with denosumab: a case report.

Authors :
Hameed M
O'Connell JE
Rogers SN
Source :
The British journal of oral & maxillofacial surgery [Br J Oral Maxillofac Surg] 2019 Sep; Vol. 57 (7), pp. 691-693. Date of Electronic Publication: 2019 Jun 21.
Publication Year :
2019

Abstract

The management of giant cell granulomas is challenging, and aggressive lesions have a high tendency to recur after enucleation alone. Based on assumptions regarding cell type and receptors, multiple pharmacological adjuncts have been used to manage them. We describe the use of denosumab, which was successfully used as a single method of treatment, suggesting that it may be a viable alternative or adjunct to operation on giant cell granulomas of the jaws.<br /> (Crown Copyright © 2019. Published by Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1532-1940
Volume :
57
Issue :
7
Database :
MEDLINE
Journal :
The British journal of oral & maxillofacial surgery
Publication Type :
Academic Journal
Accession number :
31230854
Full Text :
https://doi.org/10.1016/j.bjoms.2019.05.023