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Put the Pedal to the METTL1: Adding Internal m 7 G Increases mRNA Translation Efficiency and Augments miRNA Processing.

Authors :
Boulias K
Greer EL
Source :
Molecular cell [Mol Cell] 2019 Jun 20; Vol. 74 (6), pp. 1105-1107.
Publication Year :
2019

Abstract

Complementary papers by Zhang, Liu, and colleagues (Zhang et al., 2019) and Pandolfini, Barbieri, and colleagues (Pandolfini et al., 2019) develop new sequencing techniques that reveal that METTL1 N7-methylates internal guanosines in mRNAs and miRNAs to increase translation efficiency and miRNA processing, respectively.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1097-4164
Volume :
74
Issue :
6
Database :
MEDLINE
Journal :
Molecular cell
Publication Type :
Academic Journal
Accession number :
31226274
Full Text :
https://doi.org/10.1016/j.molcel.2019.06.004