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c-Myc steers translation in lymphoma.
- Source :
-
The Journal of experimental medicine [J Exp Med] 2019 Jul 01; Vol. 216 (7), pp. 1471-1473. Date of Electronic Publication: 2019 Jun 17. - Publication Year :
- 2019
-
Abstract
- Members of the MYC family of oncogenes are master regulators of mRNA translation. In this issue of JEM , Singh et al. (https://doi.org/10.1084/jem.20181726) demonstrate that c-Myc governs protein synthesis in lymphoma cells by interfering with SRSF1- and RBM42-mediated suppression of mRNA translation and by altering selection of translation initiation sites.<br /> (© 2019 Cargnello and Topisirovic.)
Details
- Language :
- English
- ISSN :
- 1540-9538
- Volume :
- 216
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- The Journal of experimental medicine
- Publication Type :
- Academic Journal
- Accession number :
- 31209069
- Full Text :
- https://doi.org/10.1084/jem.20190721