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Cytotoxic glycosides from the roots of Weigela x "Bristol Ruby".
- Source :
-
Fitoterapia [Fitoterapia] 2019 Sep; Vol. 137, pp. 104242. Date of Electronic Publication: 2019 Jun 13. - Publication Year :
- 2019
-
Abstract
- Seven oleanane-type glycosides were extracted and isolated by various chromatographic methods from the roots of Weigela x "Bristol Ruby" (1-7), six previously undescribed (1-6) and a known one (7). Their structures were assigned by spectroscopic analysis mainly 2D NMR and mass spectrometry (ESIMS). Selected triterpenoid glycosides (1-3, 6, 7) displayed a good cytotoxic activity against a mouse colon cancer cell line CT26.<br /> (Copyright © 2019 Elsevier B.V. All rights reserved.)
- Subjects :
- Animals
Antineoplastic Agents, Phytogenic isolation & purification
Cell Line, Tumor
Glycosides isolation & purification
Mice
Molecular Structure
Oleanolic Acid isolation & purification
Oleanolic Acid pharmacology
Phytochemicals isolation & purification
Phytochemicals pharmacology
Plant Roots chemistry
Triterpenes isolation & purification
Triterpenes pharmacology
Antineoplastic Agents, Phytogenic pharmacology
Caprifoliaceae chemistry
Glycosides pharmacology
Oleanolic Acid analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 1873-6971
- Volume :
- 137
- Database :
- MEDLINE
- Journal :
- Fitoterapia
- Publication Type :
- Academic Journal
- Accession number :
- 31202889
- Full Text :
- https://doi.org/10.1016/j.fitote.2019.104242