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Do systemic steroids increase the risk of ocular complication in uveitis patients? Focus on a Italian referral center.
- Source :
-
Clinical rheumatology [Clin Rheumatol] 2019 Oct; Vol. 38 (10), pp. 2917-2923. Date of Electronic Publication: 2019 Jun 06. - Publication Year :
- 2019
-
Abstract
- Introduction: To describe the ocular inflammatory and iatrogenic complications in a cohort of uveitic patients treated in an Italian referral centre.<br />Material and Methods: Retrospective non-comparative case series. Medical history and clinical findings of all consecutive patients referred to the uveitis center of Pisa University from January 2015 to January 2017 were reviewed. Only patients with at least three follow-up visits in our center were included in our series.<br />Results: Three hundred and eighty-nine patients were visited in our center during study period; only 142 patients (90 men and 52 female) satisfied the inclusion criteria. Mean age at presentation was 41 ± 14 years. The most common ocular feature was anterior uveitis (46%) and was mainly unilateral. A specific etiological diagnosis was established in 61% of patients. At presentation, 71.43% of patients were on medical therapy for rheumatic disease; 42.86% of patients used systemic steroids Cataract and ocular hypertension were the most common ocular complications during the study period but were not statistically related to systemic steroid treatment.<br />Conclusions: Systemic steroids treatment in uveitis patients does not seem to increase the risk of iatrogenic complications such as cataract and glaucoma. In our series, increasing age appears to be the main risk factor for cataract and glaucoma development. Key points • Cataract, ocular hypertension, and glaucoma are the most common iatrogenic complications. • Systemic steroids can be safely used in uveitis patients.
- Subjects :
- Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Cataract complications
Eye physiopathology
Female
Glaucoma complications
Humans
Inflammation
Italy epidemiology
Male
Middle Aged
Ocular Hypertension complications
Retrospective Studies
Rheumatic Diseases complications
Risk Factors
Steroids therapeutic use
Uveitis complications
Visual Acuity
Young Adult
Cataract chemically induced
Glaucoma chemically induced
Ocular Hypertension chemically induced
Rheumatic Diseases drug therapy
Steroids adverse effects
Uveitis drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1434-9949
- Volume :
- 38
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Clinical rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 31172366
- Full Text :
- https://doi.org/10.1007/s10067-019-04585-3