Back to Search
Start Over
[Effect of physical exercise on Alzheimer's disease. A sistematic review].
- Source :
-
Atencion primaria [Aten Primaria] 2020 May; Vol. 52 (5), pp. 307-318. Date of Electronic Publication: 2019 May 29. - Publication Year :
- 2020
-
Abstract
- Objective: The objective of this review is to analyze through a the scientific evidence about the effects of physical activity in patients with Alzheimer's disease (AD) as a preventive and non-pharmacological treatment.<br />Design: Systematic review.<br />Data Sources: We have identified articles from Pubmed, Science Direct, Medline and Scopus databases, with the keywords Alzheimer, Exercise, Neuroimaging, MRI, PET y Physical Activity. Selected articles: We included those studies that evaluated the effects of physical activity on Alzheimer's disease and those which also included magnetic resonance imaging or positron emission tomography with Pittsburg Compound B marker (PiB) analyzing brain atrophy or increase of the beta-amyloid deposit respectively. We excluded studies including other types of dementia, different of AD. We also excluded articles which not included neuroimaging tests, single cases or non-English language articles.<br />Data Extraction: The PRISMA quality scale was used for the critical lecture of the studies. The researchers independently assessed the articles and the discrepancies were resolved by consensus.<br />Results: We identified 75 articles, of which 23 were finally included in the review.<br />Conclusions: Most of the studies included do not allow us to know the impact of physical exercise on cognition and the cerebral structural-functional changes in patients at risk of developing AD or in patients who already have the disease. Without being able to rule out a possible beneficial effect, more studies are needed with a better design and methodological rigor that allows a better known about this association.<br /> (Copyright © 2018 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.)
Details
- Language :
- Spanish; Castilian
- ISSN :
- 1578-1275
- Volume :
- 52
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Atencion primaria
- Publication Type :
- Academic Journal
- Accession number :
- 31153668
- Full Text :
- https://doi.org/10.1016/j.aprim.2018.09.010