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Use of a 2.5% Cross-Linked Polyacrylamide Hydrogel in the Management of Joint Lameness in a Population of Flat Racing Thoroughbreds: A Pilot Study.

Authors :
de Clifford LT
Lowe JN
McKellar CD
Bolwell C
David F
Source :
Journal of equine veterinary science [J Equine Vet Sci] 2019 Jun; Vol. 77, pp. 57-62. Date of Electronic Publication: 2019 Feb 27.
Publication Year :
2019

Abstract

Osteoarthritis is one of the most common disease processes effecting equine athletes, causing up to 60% of all lameness. This prospective longitudinal study reports on the effect of treatment of carpal and metacarpophalangeal joint lameness with 2.5% cross-linked polyacrylamide hydrogel (PAAG). A total of 49 flat-racing Thoroughbreds at a single training facility were included in the study. The results show a significant improvement in lameness grades at weeks 1 (P < .01), 4 (P < .001), 12 (P < .001), and 24 (P < .001) when compared to baseline lameness at week 0. This pilot study suggests that 2.5% cross-linked PAAG is a safe and effective joint treatment for managing joint lameness in Thoroughbred racehorses and warrants further blinded and controlled studies to fully evaluate the efficacy of the 2.5% cross-linked PAAG and its mode of action.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
0737-0806
Volume :
77
Database :
MEDLINE
Journal :
Journal of equine veterinary science
Publication Type :
Academic Journal
Accession number :
31133317
Full Text :
https://doi.org/10.1016/j.jevs.2019.02.012