Adjuvant treatment of severe varicella pneumonia with intravenous varicella zoster virus-specific immunoglobulins.

Authors :: Mangioni D
Grasselli G
Abbruzzese C
Muscatello A
Gori A
Bandera A
Source :: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2019 Aug; Vol. 85, pp. 70-73. Date of Electronic Publication: 2019 May 24.
Publication Year :: 2019
Abstract: Varicella zoster virus (VZV) pneumonia is associated with significant mortality, especially in the immunocompromised host. VZV-specific immunoglobulins (VZIG) are currently used as post-exposure prophylaxis for at-risk patients, but not as adjunctive therapy. A novel case of VZV pneumonia in an immunocompromised patient, treated successfully with intravenous VZIG in combination with acyclovir, is reported here.<br /> (Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Subjects :: Acyclovir therapeutic use
Adjuvants, Immunologic administration & dosage
Administration, Intravenous
Adult
Antibodies, Viral administration & dosage
Antiviral Agents therapeutic use
Humans
Immunocompromised Host
Male
Adjuvants, Immunologic therapeutic use
Antibodies, Viral therapeutic use
Herpesvirus 3, Human immunology
Pneumonia, Viral drug therapy
Varicella Zoster Virus Infection drug therapy

Language :: English
ISSN :: 1878-3511
Volume :: 85
Database :: MEDLINE
Journal :: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Publication Type :: Academic Journal
Accession number :: 31132473
Full Text :: https://doi.org/10.1016/j.ijid.2019.05.022

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