Back to Search
Start Over
Gastroesophageal Junction Adenocarcinoma: Is There an Optimal Management?
- Source :
-
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting [Am Soc Clin Oncol Educ Book] 2019 Jan; Vol. 39, pp. e88-e95. Date of Electronic Publication: 2019 May 17. - Publication Year :
- 2019
-
Abstract
- The incidence of gastroesophageal junction (GEJ) adenocarcinomas has been rising over the past few decades, creating a need for effective therapeutic strategies. Treatment of locally advanced GEJ tumors, in particular, present a unique challenge because these tumors have generally been approached as either esophageal or gastric cancers, and thus optimal preoperative management remains uncertain. Both neoadjuvant chemoradiation and perioperative chemotherapy have been widely adopted in standard practice; however, it is unclear which approach offers the optimal outcome for the fit patient capable of receiving any planned strategy. In this review, we debate the management of locally advanced GEJ adenocarcinoma, and discuss areas of ongoing investigation which may provide more effective and individualized treatment of patients with GEJ cancers.
- Subjects :
- Clinical Decision-Making
Clinical Trials as Topic
Combined Modality Therapy adverse effects
Combined Modality Therapy methods
Disease Management
Humans
Treatment Outcome
Adenocarcinoma diagnosis
Adenocarcinoma therapy
Esophageal Neoplasms diagnosis
Esophageal Neoplasms therapy
Esophagogastric Junction pathology
Stomach Neoplasms diagnosis
Stomach Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1548-8756
- Volume :
- 39
- Database :
- MEDLINE
- Journal :
- American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
- Publication Type :
- Academic Journal
- Accession number :
- 31099690
- Full Text :
- https://doi.org/10.1200/EDBK_236827