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Congenital cutaneous pyogenic granuloma: Report of two cases and review of the literature.
- Source :
-
Journal of cutaneous pathology [J Cutan Pathol] 2019 Sep; Vol. 46 (9), pp. 691-697. Date of Electronic Publication: 2019 Jun 11. - Publication Year :
- 2019
-
Abstract
- Congenital cutaneous pyogenic granuloma is a rare benign vascular tumor with clinical and histopathological features similar to infantile hemangioma. It usually presents as a red, pedunculated and highly friable papule. On histopathological analysis, one can see a capillary vessel proliferation with lobular pattern and endothelial proliferation. The differential diagnosis is based on negativity of glucose transporter 1 (GLUT1) immunochemistry studies. We report two infants with congenital pyogenic granuloma, one with a unique cutaneous lesion and the other with multiple lesions affecting both skin and mucosal surfaces. These two cases highlight the importance of the differential diagnosis based on the GLUT1 immunochemistry analysis considering the distinct treatments required to these infant vascular tumors.<br /> (© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
- Subjects :
- Diagnosis, Differential
Female
Humans
Infant
Infant, Newborn
Male
Glucose Transporter Type 1 metabolism
Granuloma, Pyogenic congenital
Granuloma, Pyogenic diagnosis
Granuloma, Pyogenic metabolism
Granuloma, Pyogenic pathology
Neoplasm Proteins metabolism
Vascular Neoplasms congenital
Vascular Neoplasms diagnosis
Vascular Neoplasms metabolism
Vascular Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1600-0560
- Volume :
- 46
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Journal of cutaneous pathology
- Publication Type :
- Academic Journal
- Accession number :
- 31095756
- Full Text :
- https://doi.org/10.1111/cup.13496