Back to Search
Start Over
Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns.
- Source :
-
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2019 Jul; Vol. 84, pp. 44-47. Date of Electronic Publication: 2019 May 07. - Publication Year :
- 2019
-
Abstract
- The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.<br /> (Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
- Subjects :
- Anti-Bacterial Agents therapeutic use
Endocarditis, Bacterial drug therapy
Endocarditis, Bacterial microbiology
Humans
Linezolid therapeutic use
Male
Methicillin-Resistant Staphylococcus aureus genetics
Microbial Sensitivity Tests
Middle Aged
RNA, Ribosomal, 23S
Staphylococcal Infections drug therapy
Staphylococcal Infections microbiology
Anti-Bacterial Agents pharmacology
Endocarditis, Bacterial etiology
Heart Ventricles
Heart-Assist Devices adverse effects
Staphylococcal Infections etiology
Staphylococcus aureus drug effects
Staphylococcus aureus genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1878-3511
- Volume :
- 84
- Database :
- MEDLINE
- Journal :
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 31075509
- Full Text :
- https://doi.org/10.1016/j.ijid.2019.05.001